Inertial microfluidic systems have been arousing interest in medical applications due to their simple and cost- efficient use. However, comparably small sample volumes in the microliter and milliliter ranges have so far prevented efficient applications in continuous bioprocesses. Nevertheless, recent studies suggest that these systems are well suited for cell separation in bioprocesses because of their facile adaptability to various reactor
sizes and cell types. Spiral microchannels have already been shown to be capable of replacing microfilters, .extracting dead cells and debris in perfusion processes, and removing contaminant microalgae species