Magnetophoresis utilize non-uniform magnetic field for manipulation of microparticles and cells. It is a technique with little heat generation. Moreover, there is little limitation on the choice of device construction material as magnetic fields can penetrate most materials of choice for fabricating microfluidic devices such as glass and polymers.[13] Magnetophoresis is usually gentle and nondestructive for biological analyses of proteins or peptides, and even suitable for large protein complexes which tend to be broken up in traditional column chromatography. Besides, it is one approach for the separation of cells with slight or no aggression to the biophysical integrity of living cells, and can be used directly for raw biological samples with several .simple steps
